Endocrine Abstracts

Graves’ disease (GD) is a heterogeneous disorder affecting with varying degrees of severity the thyroid and eyes. This variety may suggest that complex interactions between genetic, environmental and endogenous factors influence the clinical course of GD. Although the genetic predisposition to GD is well established, the significance of genotype-phenotype correlations remains controversial. Moreover, the lack of complete phenotypic concordance in twin studies suggested th...

Introduction: Subclinical hyperthyroidism (SH) affects about 1% of world human population at least. The diagnosis of this disease leans on the laboratory criteria only: decreased of TSH and normal FT3 and FT4 concentrations. SH increases mortality mostly due to cardiovascular diseases including overload of the heart and ventricular arrhythmia. These symptoms are anticipated by increasing of left ventricular walls thickness and its mass index.<p class=...